Details for gene set NCI_IL23-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	NCI_IL23-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.7783537
Normalized Enrichment Score (NES)	-1.6917057
Nominal p-value	0.0
FDR q-value	0.009330693
FWER p-Value	0.049

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ARRB2	20806	1508	0.540	-0.0589	No
2	MALT1	6274	2207	0.289	-0.0845	No
3	CHUK	23665	2349	0.253	-0.0816	No
4	IL12RB1	3916 18582	2372	0.245	-0.0726	No
5	IKBKB	4907	2832	0.138	-0.0917	No
6	SOCS3	20131	3056	0.101	-0.0995	No
7	IL18R1	14263	3182	0.087	-0.1026	No
8	CXCL9	5099	3864	0.045	-0.1375	No
9	IL1B	14431	3930	0.043	-0.1392	No
10	IL24	976 13841	5132	0.020	-0.2031	No
11	CD4	16999	5257	0.018	-0.2090	No
12	XPO1	4172	5368	0.017	-0.2142	No
13	FBXW11	20926	5630	0.015	-0.2277	No
14	SRC	5507	5732	0.014	-0.2326	No
15	IL19	13839	7099	0.007	-0.3059	No
16	CD3E	8714	8078	0.004	-0.3584	No
17	IL17A	14289	8270	0.004	-0.3685	No
18	ITGA3	20284	8555	0.003	-0.3837	No
19	IL2	15354	8581	0.003	-0.3849	No
20	ATM	2976 19115	9513	0.001	-0.4351	No
21	NFKB2	23810	9535	0.001	-0.4362	No
22	IL17F	13992	10038	-0.000	-0.4632	No
23	IL23R	17127	10286	-0.001	-0.4765	No
24	IL12B	20918	10475	-0.001	-0.4866	No
25	ALOX12B	20825	10484	-0.001	-0.4870	No
26	IL6	16895	10534	-0.001	-0.4895	No
27	CCL2	9788	11156	-0.003	-0.5229	No
28	IKBKG	2570 2562 4908	11885	-0.005	-0.5619	No
29	IL18RAP	14262	12314	-0.007	-0.5847	No
30	PIK3R1	3170	12501	-0.008	-0.5944	No
31	RIPK2	2528 15935	12516	-0.008	-0.5948	No
32	PIK3CA	9562	13536	-0.014	-0.6492	No
33	TNF	23004	13662	-0.015	-0.6553	No
34	IL23A	19598	13729	-0.016	-0.6582	No
35	CXCL1	9044	14336	-0.025	-0.6898	No
36	BCL3	8654	14526	-0.029	-0.6988	No
37	ERC1	1013 17021 995 1136	14611	-0.032	-0.7020	No
38	STAT4	14251 9907	14999	-0.046	-0.7210	No
39	JAK2	23893 9197 3706	15078	-0.050	-0.7231	No
40	STAT5A	20664	15080	-0.050	-0.7211	No
41	TNFRSF1A	1181 10206	15409	-0.069	-0.7359	No
42	IFNG	19869	15440	-0.071	-0.7345	No
43	UBE2D3	7253	15448	-0.072	-0.7319	No
44	RELB	17942	15563	-0.083	-0.7346	No
45	NOD2	6384	15923	-0.131	-0.7485	No
46	REL	9716	16118	-0.172	-0.7519	No
47	LCK	15746	16281	-0.210	-0.7519	No
48	CYLD	18532	16309	-0.218	-0.7443	No
49	TYK2	12058 19215	16346	-0.228	-0.7368	No
50	PRKCA	20174	17118	-0.497	-0.7577	Yes
51	BIRC2	4397 4398	17163	-0.514	-0.7388	Yes
52	MAPK14	23313	17215	-0.531	-0.7195	Yes
53	NFKB1	15160	17596	-0.757	-0.7086	Yes
54	MAP3K14	11998	17649	-0.792	-0.6785	Yes
55	RELA	23783	17734	-0.859	-0.6474	Yes
56	SYK	21636	17870	-0.978	-0.6141	Yes
57	BCL10	15397	17878	-0.984	-0.5737	Yes
58	TRAF6	5797 14940	17908	-1.020	-0.5330	Yes
59	IL18	9172	18031	-1.145	-0.4920	Yes
60	TNFAIP3	19810	18051	-1.180	-0.4441	Yes
61	STAT1	3936 5524	18114	-1.257	-0.3953	Yes
62	NFKBIA	21065	18148	-1.309	-0.3428	Yes
63	MPO	5116 20710 1324	18180	-1.357	-0.2882	Yes
64	STAT3	5525 9906	18327	-1.720	-0.2247	Yes
65	RAN	5356 9691	18611	-5.793	0.0003	Yes